Gregory Toole worked in the computer industry beginning in 1983, starting as a software developer, eventually earning an MBA from the MIT Sloan School of Management, and then working in the same industry in marketing and business development.

One day while still in the midst of this successful 12-year career, and shortly after completing the Science of Mind Foundational class at East Bay Church of Religious Science in Oakland, CA, Gregory felt a strong pull to be of greater service to humanity in some way. At the time it was not clear how this was to be, but it was very clear that his corporate career was complete and that he was to embark on something new.

He left that career in 1995 to discover what this new calling would be. Shortly thereafter he discovered a love of working with youth. He became the first Executive Director of a new non-profit organization called National Youth Enterprise Institute, doing youth development in Oakland, California. He found much success and fulfillment in this work.

In 1998 he became a Licensed Religious Science Practitioner, and in 2001, his clarity sharpened on his calling and he entered the ministerial training program of Holmes Institute School of Consciousness Studies. Shortly after entering the program he left the non-profit organization to embark on various forms of ministry, including teaching classes and workshops, speaking, and spiritual counseling.

In his final year of ministerial school he became the Interim Spiritual Leader for the Center for Spiritual Living in Davis, California, where he became the Senior Minister upon graduation. During his time in this community that had been without a minister for many years, he graduated their first group of practitioners and established a vibrant spiritual community.

After five years with this spiritual community, in 2008 Gregory accepted the position of Ecclesiastical Leader for United Centers for Spiritual Living where he oversees and leads the activities and programs serving its many centers, churches, practitioners, and ministers. In this role he is responsible for all of the Ecclesiastical departments, including Education; Holmes Institute; Growth, Expansion, and Ministerial Support (GEMS); International Youth and Family Ministries; World Ministry of Prayer; and several volunteer core groups.